Category

Cholesterol

Cholesterol is one of the most important molecules in the human body and is most commonly known for the role it plays in atherosclerotic cardiovascular disease (ASCVD) — the number one killer in the developed world.

Below is a collection of content that goes into great depth about cholesterol, the role cholesterol plays with respect to heart disease, why there is no ‘good’ or ‘bad’ cholesterol, and why apoB is actually a superior metric for assessing CVD risk over cholesterol.

#129 – Tom Dayspring, M.D.: The latest insights into cardiovascular disease and lipidology

Atherogenic lipoproteins are really the issue behind clinical atherosclerotic vascular disease. … The data has just become so overwhelming.” —Tom Dayspring

#24 – Tom Dayspring, M.D., FACP, FNLA – Part V of V: Lp(a), inflammation, oxLDL, remnants, and more

“Use the correct terminology with everything.” –Tom Dayspring

#23 – Tom Dayspring, M.D., FACP, FNLA – Part IV of V: statins, ezetimibe, PCSK9 inhibitors, niacin, cholesterol and the brain

“This is what it ultimately comes down to – and it’s the way you practice – you’ve got to individualize everything.” –Tom Dayspring

#22 – Tom Dayspring, M.D., FACP, FNLA – Part III of V: HDL, reverse cholesterol transport, CETP inhibitors, and apolipoproteins

“Here’s something that’s going to shock you: in an average person, anywhere from 30 to 60 percent of the cholesterol in that LDL particle arrived via an HDL particle.” –Tom Dayspring

#21 – Tom Dayspring, M.D., FACP, FNLA – Part II of V: Lipid metrics, lipid measurements, and cholesterol regulation

“If you learn nothing else today, the first thing is, lipids, for the most part, go nowhere in the human body unless they’re a passenger inside a lipoprotein.” –Tom Dayspring

#20 – Tom Dayspring, M.D., FACP, FNLA – Part I of V: an introduction to lipidology

“Illustrating things made me understand . . .  I just learned by illustrating.” –Tom Dayspring

Narrative glossary: lipids

A companion post for the podcast episodes with Thomas Dayspring, M.D., FACP, FNLA (October 15-19, 2018).

#19 – Dave Feldman: stress testing the lipid energy model

“I am on a journey of science, not of advocacy: I’m going to be quite a skeptic.”  —Dave Feldman

Transcript — The Drive — Dave Feldman

Transcript of episode 19 of The Drive with Peter Attia, released October 8, 2018.

Statins, Lp(a), and upcoming podcast guests

In other words, statins are not addressing the associated risk in patients with an elevated Lp(a), and this population represents about 25% of those with previous CVD or an indication for statins.

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