September 30, 2018

Weekly Emails

AMA, Alzheimer’s, podcast rec, and NAD rec

Spoiler alert: Not sure taking NAD precursors orally is doing much beyond enriching the companies that make them.

Just finished recording an AMA (#3) and a podcast with Richard Isaacson this week. For the AMA, we broke out the camcorder, so we’ll see how the video turns out in addition to the audio. Lots of good questions addressed. (Submit questions here if you have one.)

Richard is an Alzheimer’s disease (AD) specialist and the director of the Alzheimer’s Prevention Clinic at Weill Cornell. We covered the role of APOE in AD, why we think the prevalence of AD is higher in females, and what people can do to reduce the risk of AD, among other important topics. Expect this one out around October.

Killing some time in the airport I listened to Sam Harris’s Waking Up podcast with guest Jonathan Haidt (#137 – Safe Space). It is informative (and upsetting) on a number of levels. Here are few:

  • Approach to helping our kids be less fragile
  • How social media is crushing nuance
  • Tragedy of what happened to Mary Spellman
  • The growing hostility to free speech among young adults

Lastly, I read a paper (behind a paywall, unfortunately) in Cell by Josh Rabinowitz and colleagues on NAD (nicotinamide adenine dinucleotide) flux that was well-done and revealing (and freakin’ long—took a few hours to read). This is 100% going to be a future podcast topic for folks interested in NAD, NR (nicotinamide riboside), and the supplements they show up in (Basis, Tru Niagen). Spoiler alert: Not sure taking NAD precursors orally is doing much beyond enriching the companies that make them.

– Peter

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