Family Medical History & Genetics

When patients join my practice, one of their first exercises is to gather a detailed family medical history. We want to know everything knowable about their mother, father, grandparents, aunts, uncles, and siblings. Although I recognize this is not possible for everyone, for those who are able to gather this information, it can help reveal patterns that may prove critical for your longevity journey. The more data you collect, the more likely you are to understand what’s really at the root of the genetic template that you inherited. 

Below is a collection of audio clips and podcasts all about genetics, what to look for when gathering your family history, how genetics can influence your risk of certain diseases, and even the potential role of genetics in determining one’s success in a given discipline.

Family Medical History & Genetics

Peter on what to ask when gathering a family medical history

This audio clip is from AMA #15: Real-world case studies, originally released on August 17, 2020.

PCSK9 inhibitors

The genetics of PCSK9i nonresponders

A recent case study shines light on why some individuals are resistant to PCSK9 inhibitors. 

How useful are home DNA kits?

This video clip is from AMA #8: DNA tests, longevity genes, metformin, fasting markers, salt, inflammation, and more, originally released…

What is the role of genetics in determining one’s work ethic and success in a given discipline?

This clip is from episode #183, James Clear: Building & Changing Habits, originally released on November 8, 2021.  

Peter on Alzheimer’s disease prevention and the latest on APOE4

This clip is from episode #202, Peter on nutrition, disease prevention, sleep, and more, originally released on April 11, 2022….

Qualys #241 – The genetic gift of centenarians

This episode of The Qualys is from podcast #35, Nir Barzilai, M.D.: How to tame aging, which was originally released on January 7, 2019.

#138 – Lauren Miller Rogen and Richard Isaacson, M.D.: Alzheimer’s disease prevention—patient and doctor perspectives

“Believe it or not, there are 46 million Americans with Alzheimer’s disease in their brain right now, but no symptoms.” — Richard Isaacson

#124 – AMA #15: Real-world case studies—metabolic dysregulation, low testosterone, menopause, and more

As a follow up to AMA #14 where Peter explained his framework for analyzing labs, this “Ask Me Anything” (AMA)…

#67 – AMA #8: DNA tests, longevity genes, metformin, fasting markers, salt, inflammation, and more

“If you are genetically blessed to become a centenarian, the gift you got is that you have genes that delay your receipt of chronic disease by what appears to be about 20 years.” — Peter Attia

#35 – Nir Barzilai, M.D.: How to tame aging

“I think the prevention of aging is really a good place to be. . .and I think life is going to be very different in the next decade with our advances.” —Nir Barzilai

#18 – Richard Isaacson, M.D.: Alzheimer’s prevention

“Anyone with a brain is at risk for Alzheimer’s.” —Richard Isaacson

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