Medications & supplements

AMA

Pros and cons of GLP-1 weight loss drugs and metformin as a geroprotective agent

Ep. #246 (AMA #45)
Medications & supplements

Free Article

Lean mass loss on GLP-1 receptor agonists: a downside of the “miracle drugs”

Risks

Free Article

Antitumor mRNA vaccines are cause for optimism

Exercise

Guest Episode

Training principles for mass and strength, changing views on nutrition, creatine supplementation, and more

Ep. #235 with Layne Norton, Ph.D.
Medications & supplements

Free Article

NR supplements: wasted money may not be the only risk with these questionable “anti-aging” drugs

Medications & supplements

Guest Episode

Ketamine: Benefits, risks, and promising therapeutic potential

Ep. #220 with Celia Morgan, Ph.D.
Medications & supplements

Free Article

Can cocoa help prevent cardiovascular death?

Nutrition

AMA

Fruits & vegetables—everything you need to know

Ep. #211 (AMA #36)
Medications & supplements

The difference between a 'clean' drug and a 'dirty' drug

Risks

Guest Episode

Lp(a) and its impact on heart disease

Ep. #210 with Benoît Arsenault, Ph.D.
Sleep

Guest Episode

How fasting can impact sleep

with Matthew Walker, Ph.D.
Longevity

Guest Episode

Are there “biomarkers” for aging?

with Matt Kaeberlein, Ph.D.
Longevity

AMA

"Anti-Aging" Drugs — NAD+, metformin, & rapamycin

Ep. #207 (AMA #35) with Matt Kaeberlein, Ph.D.
Longevity

Guest Episode

About TAME: A Metformin Anti-Aging Clinical Trial

with Nir Barzilai, M.D.
Exercise

Free Article

Are nitrates the next big thing for athletic performance?

Longevity

Guest Episode

Centenarians, metformin, and longevity

Ep. #204 with Nir Barzilai, M.D.
Other tactics, tools, & treatments

Free Article

Is cold exposure beneficial for metabolic health?

Risks

AMA

What Causes Heart Disease?

Ep. #203 (AMA #34)
Medications & supplements

Free Article

Can a father's metformin cause birth defects in his sons?

Sleep

Guest Episode

Do THC and CBD help you sleep?

with Matthew Walker Ph.D.
Exercise

Guest Episode

Deep dive back into Zone 2

Ep. #201 with Iñigo San-Millán, Ph.D.
Nutrition

AMA

Hydration—electrolytes, supplements, sports drinks, performance effects, and more

Ep. #200 (AMA #33)
Nutrition

Guest Episode

The science of obesity & how to improve nutritional epidemiology

Ep. #197 with David Allison, Ph.D
Exercise

AMA

Exercise, squats, deadlifts, BFR, and TRT

Ep. #196 (AMA #32)