Category

Nutritional Biochemistry

I often get asked, ‘Which diet works best?’. In my view, this is simply the wrong question. Nutritional biochemistry is a powerful lever in our longevity toolkit, but it is much more than fad diets or the number on the bathroom scale. A better question might be, “how can I use nutrition to support my metabolic health?”

Reframing the goal toward metabolic health is a critical starting point. From there, you can combine general principles of nutrition science (such as how much protein you need) with personalization tactics (such as using a CGM to monitor glucose levels) to build a nutrition plan that makes sense for you.

See the collection of audio clips, podcasts, and articles below to learn more about my nutrition and fasting framework.

#283 ‒ Gut health & the microbiome: improving and maintaining the microbiome, probiotics, prebiotics, innovative treatments, and more | Colleen Cutcliffe, Ph.D.

You start out almost like a blank slate, you get a lot more diverse, and then as we age, you start to lose that diversity and therefore some key functions in the microbiome.” —Colleen Cutcliffe

Why is it so difficult to determine how nutrition impacts dementia risk?

When it comes to nutrition research, neither observational nor interventional studies have been able to tell the full story. A report by the Nutrition for Dementia Prevention Working Group offers ideas for improving both.

Sugar substitutes: deep dive into the pros, cons, available options, and impact on metabolic health

Sugar substitutes offer sweet taste with minimal calories, yet they remain controversial. How well do they solve the problems associated with traditional sugar, and where do they fall short?

How does aging increase risk of dehydration?

Aging weakens the regulatory systems for maintaining water balance, necessitating more conscious oversight of fluid intake to prevent dehydration.

The cases for and against dietary protein for healthy aging

An endeavor to settle the debate of high- vs. low-protein diets for increasing lifespan and healthspan

Does carbohydrate load impact the balance between fat storage and oxidation?

A study investigated the effects of different dietary levels of carbohydrates on mitochondrial respiration, but mechanistic conclusions are premature.

Don’t drink and science: why a study on the cognitive effects of wine and cheese is sheer stupidity

A study claiming that daily consumption of cheese and wine may improve long-term cognition seems more like a bad joke than reliable science.

#252 ‒ Latest insights on Alzheimer’s disease, cancer, exercise, nutrition, and fasting | Rhonda Patrick, Ph.D.

My perspective has shifted as any scientist that’s following data should… When new data comes out, you have to reassess things.” —Rhonda Patrick

Is a recent clinical trial enough to support the use of semaglutide in treating adolescent obesity?

The imperative for effective weight management strategies in children and teens is clear, but in our desperation for effective obesity treatments, are we allowing ourselves to be too shortsighted on testing?

More hype than substance: erythritol and cardiovascular risk

A newly-published study caught public attention by reporting an association between the common sweetener erythritol and increased risk of heart attack and stroke, but there’s more to the story.

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