#310 – The relationship between testosterone and prostate cancer, testosterone replacement therapy, and tools for predicting cancer aggressiveness and guiding therapy | Ted Schaeffer, M.D., Ph.D.
“There’s no evidence that says exogenous T replacement causes acceleration or propagation of someone’s prostate cancer.” —Ted Schaeffer
#309 ‒ AI in medicine: its potential to revolutionize disease prediction, diagnosis, and outcomes, causes for concern in medicine and beyond, and more | Isaac Kohane, M.D., Ph.D.
“What I’m excited about is the opportunity for new businesses and new ways of delivering to patients insights that are data-driven.” —Zak Kohane
#308 – AMA #61: Sun exposure, sunscreen, and skin health: relationship between sun exposure and skin cancer, vitamin D production, and photoaging, how to choose a sunscreen, and more
“This is the beginning of a type of technology that I hope, over the coming decade, can make screening, especially for melanoma, to be a more effective tool.” —Peter Attia
#307 ‒ Exercise for aging people: where to begin, and how to minimize risk while maximizing potential | Peter Attia, M.D.
“The name of the game is play the game and stay in the game forever. And so we are really looking to minimize injury here and we’re looking to minimize burnout.” —Peter Attia
#306 – AMA #60: preventing cognitive decline, nutrition myths, lowering blood glucose, apoB, and blood pressure, and more
“Metabolic health, first and foremost, is the goal of nutrition.” —Peter Attia
#305 ‒ Heart rate variability: how to measure, interpret, and utilize HRV for training and health optimization | Joel Jamieson
“The older you get… you have to be much more acutely aware of what your body can and can’t do. And that’s part of what HRV can help you understand.” —Joel Jamieson
#304 – NEW: Introducing quarterly podcast summaries – Peter shares his biggest takeaways on muscle protein synthesis, VO2 max, toe strength, gut health, and more
“Getting a high VO2 max and being very strong are very hard to do. They take a long time. Everybody can do them, but they can’t be done quickly and easily, so therefore, they are the tip of the spear.” —Peter Attia
#303 – A breakthrough in Alzheimer’s disease: the promising potential of klotho for brain health, cognitive decline, and as a therapeutic tool for Alzheimer’s disease | Dena Dubal, M.D., Ph.D.
“I have this dream that people might be able someday to benefit from klotho, this factor that naturally circulates in our body, that helps with longevity, that helps with other organ systems and enhances the brain.” —Dena Dubal
#302 – Confronting a metabolic epidemic: understanding liver health and how to prevent, diagnose, and manage MAFLD and liver disease | Julia Wattacheril, M.D., M.P.H.
“The average person you’re seeing with MASLD is much more at risk for cardiovascular-related outcomes and malignancy-related outcomes from their metabolic health than they are for liver-related risks.” —Julia Wattacheril
#301 – AMA #59: Inflammation: its impact on aging and disease risk, and how to identify, prevent, and reduce it
“Inflammation really becomes chronic once it’s persisted for several months, but it can persist for much longer than that.” —Peter Attia