Risks

Podcast Episode

Prostate cancer screening: why current PSA guidelines are failing men and how modern tools improve early detection and save lives

Ep. #388
Risks

Free Article

Prostate cancer: a PSA on PSA

Medications & supplements

AMA

Peptides—evaluating the science, safety, and hype in a rapidly growing field

Ep. #387 (AMA #83)
Understanding science

Free Article

Research Worth Sharing, April 2026 Edition

Other tactics, tools, & treatments

AMA

Aging clocks—what they measure, how they work, and their clinical and real-world relevance

Ep. #386
Medications & supplements

Free Article

Updated cardiovascular guidelines—statin use in patients as young as 30

Nutrition

Premium Article

Thinking in trade-offs: a necessary antidote to diet tribalism

Risks

Free Article

Protect the eyes, protect the brain—a potentially simple lever for dementia risk

Ask Me Anything (AMA)

AMA

Applying the tools of longevity in the real world: disease prevention, DEXA scans, artificial sweeteners, injury recovery, stability training, habit formation, protein intake and mTOR activation, and more

Ep. #385 (AMA #82)
Understanding science

Free Article

When sophisticated models meet questionable premises

Risks

Podcast Episode

Special episode — Obicetrapib: The CETP inhibitor with cardiovascular benefits and potential Alzheimer's prevention

Ep. #384
Risks

Free Article

An intriguing case of “exceptional resilience” against dementia

Longevity

AMA

Biological aging tests, longevity training, emerging therapies, GLP-1 RAs, sun exposure, and more

Ep. #383 (AMA #81)
Risks

Free Article

A failed endpoint is not a failed technology

Longevity

AMA

Longevity optimization through strength benchmarks, VO₂ max targets, nutrition principles, brain health, supplements, GLP-1 RAs, wearables, and more

Ep. #382 (AMA #80)
Risks

Premium Article

Does lowering cholesterol harm the brain?

Medications & supplements

Premium Article

GLP-1 Drugs Fail to Slow Cognitive Decline in Alzheimer’s Disease

Medications & supplements

Free Article

Metformin misses the mark?

Medications & supplements

Premium Article

Navigating the complex relationship between statins, GLP-1, and glycemic control

Risks

Free Article

The absence of atherosclerosis is not an excuse to ignore heart attack symptoms—especially for women

Nutrition

Guest Episode

The seed oil debate: are they uniquely harmful relative to other dietary fats?

Ep. #380 with Layne Norton, Ph.D.
Exercise

Free Article

Why this exercise study isn’t answering the question you think it is

Exercise

AMA

A guide to cardiorespiratory training at any fitness level to improve healthspan, lifespan, and long-term independence

Ep. #379 (AMA #79)
Risks

Free Article

Pitting facts against sensationalism regarding the role of LDL cholesterol in ASCVD