Email Archive

• Can a new drug mimic the effects of exercise on bone and muscle? (3/25/2023)
• Finding the right fit in a psychotherapist (3/18/2023)
• A recent metformin study casts doubts on longevity indications (3/11/2023)
• More hype than substance: erythritol and cardiovascular risk (3/4/2023)
• How much control can we really have in studies on animals? (2/25/2023)
• Lean mass loss on GLP-1 receptor agonists: a downside of the “miracle drugs” (2/18/2023)
• Screen time and children’s cognition: a question of context (2/11/2023)
• The dangers of “healthy” addictions (2/4/2023)
• Twenty years after the Columbia disaster, what can we learn from the mistake of ignoring problems? (1/28/2023)
• To reduce appetite, skip late-night snacks (1/21/2023)
• Non-caffeine components of coffee and their effects on neurodegenerative diseases (1/14/2023)
• Antitumor mRNA vaccines are cause for optimism (1/7/2023)
• The Safety Debate Between Manual and Automatic Transmissions (12/31/2022)
• Understanding nature’s effects on stress requires more than intuition (12/17/2022)
• NR supplements: wasted money may not be the only risk with these questionable “anti-aging” drugs (12/10/2022)
• Book release date announcement (12/3/2022)
• Does solitude equate to loneliness? (11/26/2022)
• When it comes to medical advice, is less always more? (11/19/2022)
• Can an annual flu vaccine reduce your risk of Alzheimer’s disease? (11/12/2022)
• Reassuring new data on statin-induced Lp(a) elevation (11/5/2022)
• Modern Vampirism: “Young Blood” Transfusions (10/29/2022)
• Muscle Mass and Cognitive Function (10/22/2022)
• Confusion over results of a recent colonoscopy trial (10/15/2022)
• How horror may reduce anxiety and improve mental well-being (10/8/2022)
• The genetics of PCSK9i nonresponders (10/1/2022)
• A “miracle pill” for hangover prevention? (9/24/2022)
• The Epidemic on the Road (9/17/2022)
• Small steps toward improving research reliability (9/10/2022)
• Adding context to the Alzheimer’s disease research fraud charges (9/3/2022)
• Prioritizing “real friends” over “deal friends” (8/27/2022)
• Different effects of fat- vs. carbohydrate-restriction on neural reward signaling (8/20/2022)
• Vitamin D(éjà vu): new study, same old problems (8/13/2022)
• First Case of Human PCSK9 Gene-Editing (8/6/2022)
• Avoiding Injury Part II: Grip Strength (7/30/2022)
• Avoiding Injury Part I: Eccentric Strength (7/23/2022)
• And the 2050 World Cup champions are… robots? (7/16/2022)
• Cumulative effects of LDL-C reduction in mitigating cardiovascular risk (7/9/2022)
• The Drive podcast turns 4 (7/2/2022)
• Can cocoa help prevent cardiovascular death? (6/25/2022)
• A pilot immunotherapy trial is one step on a long road toward curing cancer (6/18/2022)
• Why do we lose muscle strength with age? (6/11/2022)
• Why do women have lower alcohol tolerance than men? (6/4/2022)
• Dangerous messaging around a recent SIDS study (5/28/2022)
• Do helmets give cyclists a false sense of security? (5/21/2022)
• For triglycerides, “normal” may not be “optimal” (5/14/2022)
• Are nitrates the next big thing for athletic performance? (5/7/2022)
• Does walking 10 minutes per day extend your life? (Hint: No.) (4/30/2022)
• Is cold exposure beneficial for metabolic health? (4/23/2022)
• Can a father’s metformin cause birth defects in his sons? (4/16/2022)
• How deadly is type 2 diabetes? (4/9/2022)
• Why a recent study hasn’t shaken my faith in statins (4/2/2022)
• Does PR Lotion really improve exercise performance? (3/26/2022)
• The Epidemic of Martiomania (3/19/2022)
• Are “safe” levels of air pollution really safe? (3/12/2022)
• A broader perspective on lung cancer (3/5/2022)
• Nutritional epidemiology: abolition vs defending the status quo (2/26/2022)
• A suicide safety net at the Golden Gate Bridge (2/19/2022)
• Hyperbolic discounting: friend and foe of goal achievement (2/12/2022)
• Low LDL cholesterol and neural development (2/5/2022)
• Not another COVID newsletter (1/29/2022)
• Why I’m for COVID vaccines, but against vaccine mandates. (1/23/2022)
• Are we oversimplifying Alzheimer’s disease? (1/15/2022)
• How do you move forward after making a fatal mistake? (1/8/2022)
• Is lab-grown meat the ‘meat of the future’? (1/2/2022)
• What a dead salmon can teach us about how we use machines (12/25/2021)
• How to Handle a Phishing Email (12/18/2021)
• Is lack of curiosity an age-related condition? (12/11/2021)
• Ketogenic Diets: Not For Everyone? (12/5/2021)
• Does Exercise Affect Lifespan? (11/28/2021)
• A Game Plan for Healthy Enjoyment of the Holidays (11/21/2021)
• How to Make Better Decisions: Understanding Bias vs. Noise (11/14/2021)
• Does fish oil cause cardiac arrhythmia in high-risk individuals? (11/7/2021)
• Does skipping breakfast increase the risk of an early death? Part II (10/31/2021)
• Does skipping breakfast increase the risk of an early death? Part I (10/24/2021)
• Ten errors in randomized experiments (10/17/2021)
• Is alternate-day fasting superior to calorie restriction for fat loss in lean adults? (10/10/2021)
• Morning vs evening exercise (10/3/2021)
• Does low cholesterol cause cognitive impairment? Part II (9/26/2021)
• Does low cholesterol cause cognitive impairment? Part I (9/19/2021)
• Rapamycin risks? (9/12/2021)
• The road to 9/11, and 20 years after (9/5/2021)
• How should we do drugs now?; searching for a Bob Ross painting (8/22/2021)
• Alternative perspectives on drug use and addiction (8/15/2021)
• What would you do if you won the lottery? (8/8/2021)
• How long can we live?; suggested listening (8/1/2021)
• A new frontier for early cancer detection? (7/25/2021)
• Rapamycin: one of my favorite stories; Ryan Lochte’s flip side on missing Olympic redemption (7/18/2021)
• Protecting against hearing loss (7/11/2021)
• Three years behind the podcast mic (7/4/2021)
• Brain implants and identity; recovering a fallen Marine’s Purple Heart (6/27/2021)
• Are continuous glucose monitors a waste of time for people without diabetes? (6/20/2021)
• A hope for treating Alzheimer’s disease? (6/13/2021)
• D-Day: June 6, 1944 (6/6/2021)
• MDMA for PTSD? (5/30/2021)
• Psilocybin for depression? (5/23/2021)
• Does NMN improve metabolic health in humans? (5/9/2021)
• Was COVID-19 the only culprit behind the extraordinary increase in deaths last year? (5/2/2021)
• What gives Rice Krispies their pop and my related experiment (4/25/2021)
• Cicada awakening (4/18/2021)
• mRNA vaccine technology (4/11/2021)
• Easter weekend egg boxing (4/4/2021)
• Metformin and COVID-19 mortality risk; a timeline of Kobe’s last day (3/28/2021)
• Commemorating Ayrton Senna’s birthday (3/21/2021)
• Early risk assessment markers to delay cardiovascular disease (3/14/2021)
• A scientific journal’s injustice; the true payoff of deliberate practice (3/7/2021)
• Promise and challenges for psilocybin and MDMA use in treatment (2/28/2021)
• A win for Topo Chico; COVID-19 vaccine second dose (2/21/2021)
• Should you get the COVID-19 vaccine? (2/14/2021)
• Lung cancer in never smokers; Diagnosing a medical case study (2/7/2021)
• Does vitamin D deficiency raise COVID-19 risk? (1/31/2021)
• The psychology of fact checking; A mother’s essay on her own sobriety (1/24/2021)
• Do I really need 8 glasses of water a day? (1/17/2021)
• Britain’s COVID-19 vaccine gamble; The upside of quitting (1/10/2021)
• More than a meme (1/3/2021)
• Psychedelic Santa; The dog that didn’t bark (12/27/2020)
• Should we still be worried about MSG? (12/20/2020)
• A few things worth checking out: 12-13-2020 (12/13/2020)
• Replacing sugar with allulose (12/6/2020)
• A few things worth sharing: 11-29-2020 (11/29/2020)
• Q&A on Alzheimer’s disease drug therapy with Dr. Richard Isaacson (11/22/2020)
• Masking emotion in the age of COVID-19 (11/15/2020)
• A few things worth sharing: 11-08-2020 (11/8/2020)
• Teaching science through the lens of discovery (11/1/2020)
• A few things worth sharing: 10-25-2020 (10/25/2020)
• Time-restricted eating: efficacy versus effectiveness (10/18/2020)
• Topo Chico (10/11/2020)
• A few things worth sharing: 10-04-2020 (10/4/2020)
• Colorectal cancer screening (9/27/2020)
• I need your help! (9/20/2020)
• A few things worth sharing: 09-13-2020 (9/13/2020)
• Randomized controlled trials: when the gold standard leaves you with fool’s gold (9/6/2020)
• A few things worth sharing: 08-30-2020 (8/30/2020)
• Normative errors and Surgisphere (8/23/2020)
• A few things worth sharing: 08-16-2020 (8/16/2020)
• Robin Williams (8/9/2020)
• The power of no (7/26/2020)
• How to find a good doctor (7/12/2020)
• Breakfast: a legacy of cereal…and sin? (6/28/2020)
• COVID framework: How does this thing end? (6/21/2020)
• SARS-CoV-2 and the host response: psychological stress (6/7/2020)
• The importance of red teams (5/24/2020)
• Multiple problems with a study linking proximity to major roads to dementia, Parkinson’s disease, Alzheimer’s disease, and MS (3/8/2020)
• The red meat and plant-based recommendation wars (3/1/2020)
• The pleasure of finding things out (2/23/2020)
• Alzheimer’s disease and glucose metabolism (2/16/2020)
• The killer(s) on the road: reducing your risk of automotive death (2/9/2020)
• Making sense of tragedy (2/2/2020)
• Nobel retractions (1/26/2020)
• Intermittent fasting (1/19/2020)
• My nutritional framework (1/12/2020)
• A new year (1/5/2020)
• Why is life expectancy in the US declining? (12/29/2019)
• Measuring cardiovascular disease risk and the importance of apoB (12/22/2019)
• Can fasting help athletes hold their breath longer? (12/8/2019)
• Book update (12/1/2019)
• Coronary artery calcium scan (11/24/2019)
• LDL-C & systolic blood pressure and lifetime risk of cardiovascular disease (11/10/2019)
• Is ditching meat a “game-changer” for your health? (11/3/2019)
• Is diet soda more dangerous than sugar-sweetened beverages? (10/20/2019)
• Metformin and exercise – déjà vu all over again? (10/13/2019)
• Am I fooling myself? (10/6/2019)
• Did a recent study show we can reverse aging? (9/29/2019)
• Hormone therapy and breast cancer? (9/22/2019)
• Can you reverse your biological age? (9/15/2019)
• Alternate Day Fasting (9/8/2019)
• Can you maintain muscle during fasting? (9/1/2019)
• Can you preserve lean body mass during “semi-starvation?” (8/25/2019)
• What can you prove? (8/18/2019)
• What if you never felt pain or anxiety? (8/11/2019)
• Fasting and cancer (8/4/2019)
• Cortisol and cross-pollination (7/28/2019)
• Conspiracy theory theories: July 20, 1969 (7/21/2019)
• Fast-breaking without glucose spiking (7/14/2019)
• Is there an optimal window of time-restricted feeding? (7/7/2019)
• European Vacation (6/30/2019)
• Metformin and exercise (6/23/2019)
• A hidden blockbuster drug for Alzheimer’s disease? (6/16/2019)
• Good docs (6/9/2019)
• Mind. Blown. (6/2/2019)
• The Sound of Silence (5/26/2019)
• Feeling entitled (5/19/2019)
• The Bad Science Behind ‘Skipping Breakfast’ (5/12/2019)
• You can win (5/5/2019)
• Targeting aging (4/28/2019)
• David Brooks and the quest for a moral life (4/21/2019)
• Trauma (4/14/2019)
• My view on wearables (4/7/2019)
• Driving while distracted (3/31/2019)
• Why am I such a knucklehead? (3/24/2019)
• How to fight suicide (3/17/2019)
• The mouse trap: lost in translation? (3/10/2019)
• Red meat, cancer, push-ups, and CVD (3/3/2019)
• Timely (2/24/2019)
• Ketones, fasting, and muscle loss (2/17/2019)
• Does Dad’s stress get passed along to his children? (2/10/2019)
• I’m suffering from the thought of suffering (2/3/2019)
• A radical new approach to Alzheimer’s? (1/27/2019)
• Wanna know what keeps me up at night? (1/20/2019)
• May I have your attention? (1/13/2019)
• Another name for madness (1/6/2019)
• Thinking in bets (12/30/2018)
• Predicting the future (12/23/2018)
• A new class of drugs to treat depression (12/16/2018)
• How to make better decisions (12/9/2018)
• Perspective and inspiration (12/2/2018)
• The art and science of screen time (11/25/2018)
• A moment of Zen and the importance of perspective (11/18/2018)
• The placebo effect (11/11/2018)
• Reading, resveratrol, and coffee (11/4/2018)
• Easter Island, inflammation, and ask me anything (10/28/2018)
• 1 in 10 people lack access to clean water (10/21/2018)
• A doctor with 1 million patients (10/14/2018)
• Statins, Lp(a), and upcoming podcast guests (10/7/2018)
• AMA, Alzheimer’s, podcast rec, and NAD rec (9/30/2018)
• Alzheimer’s prevention and the most important thing (9/30/2018)
• This Bud’s for you? Don’t mix alcohol with epidemiology (9/23/2018)
• Boston: Pearl Jam, Seyfried, Sinclair, and more (9/9/2018)
• The importance of sleep (9/2/2018)
• My visit to prison and is a “low-carb” diet going to shorten your life? (8/26/2018)
• Dunning, Kruger, and the opioid epidemic (8/19/2018)
• Salmon recipe (and mTOR) (8/12/2018)
• Robin Williams, Globalism on the brink, rapamycin and lifespan (8/5/2018)
• The Nothingburger and my favorite interview (7/29/2018)
• Fasting and conserving energy (7/22/2018)
• The keto buffet (7/15/2018)
• Living with Alzheimer’s (7/8/2018)
• Arrogance, humility, and the podcast launch (7/1/2018)
• Podcast is up! (6/24/2018)
• Podcast, AMA, Lp(a), and Dr. Rosenrosen (6/17/2018)
• I don’t want to talk about it… (6/10/2018)
• Breaking2 (6/3/2018)
• Does it help to know your coronary artery calcium score? (5/27/2018)
• Comedy plus time… (5/20/2018)
• Simulators, treating depression, and management of T1D with diet (5/13/2018)
• MDMA and zero LDL-C (5/6/2018)
• The Joe Rogan Experience and exploring forgiveness (4/29/2018)
• Are you living for your résumé or your eulogy? (4/22/2018)
• Down the rabbit hole (4/15/2018)
• Studying studies … and Steve Largent (4/8/2018)
• Remembering Ramanujan, Marvelous Marvin Hagler, and a new podcast (4/1/2018)
• 110 years of mortality: making progress? (3/25/2018)
• Calorie restriction? (3/18/2018)
• Sunday drive (3/11/2018)
• The importance of metabolic syndrome and the man behind it (3/4/2018)
• This is water (2/25/2018)
• The Cosmos is all that is or ever was or ever will be… (2/18/2018)
• Fat, cancer, discomfort, and giving (2/11/2018)
• The power of second chances and the Super Bowl (2/4/2018)
• Back to the future (1/28/2018)
• Breaking the cycle of pain and shame (1/21/2018)
• A big predictor of heart disease risk that most doctors don’t screen for (1/14/2018)